Artificial light sources as light pollutant of humans melatonin suppression
نویسندگان
چکیده
منابع مشابه
Blue light from light-emitting diodes elicits a dose-dependent suppression of melatonin in humans.
Light suppresses melatonin in humans, with the strongest response occurring in the short-wavelength portion of the spectrum between 446 and 477 nm that appears blue. Blue monochromatic light has also been shown to be more effective than longer-wavelength light for enhancing alertness. Disturbed circadian rhythms and sleep loss have been described as risk factors for astronauts and NASA ground c...
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Retinal light exposures can decrease melatonin production at night. Since nocturnal melatonin suppression by light has been implicated as an endocrine disruptor and linked to certain diseases, such as diabetes, obesity and cancer, it is important to be able to estimate a threshold light level needed to reliably suppress melatonin. The present study was designed to develop a working threshold fo...
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The retina drives various non-image-forming photoresponses, including circadian photoentrainment and pupil constriction. Previous investigators showed that in humans, photic suppression of the clock-controlled hormone melatonin is most sensitive to 460-nm blue light, with a threshold of ~12 log photons cm(-2) s(-1). This threshold is surprising because non-image-forming vision is mediated by in...
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Circadian rhythm disturbances parallel the increased prevalence of sleep disorders in older adults. Light therapies that specifically target regulation of the circadian system in principle could be used to treat sleep disorders in this population. Current recommendations for light treatment require the patients to sit in front of a bright light box for at least 1 hour daily, perhaps limiting th...
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Over the past few years, we have shown that the surge of melatonin in the circulation during darkness represents a potent oncostatic signal to tissue-isolated rat hepatoma 7288CTC, which is an ER+ adenocarcinoma of the liver. This oncostatic effect occurs via a melatonin receptor-mediated suppression of tumor cAMP production that leads to a suppression of the tumor uptake of linoleic acid (LA),...
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ژورنال
عنوان ژورنال: Photonics Letters of Poland
سال: 2019
ISSN: 2080-2242
DOI: 10.4302/plp.v11i3.925